TOLAZAMIDE
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1.What is the TOLAZAMIDE ?
Tolazamide
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4083-64-1
Tosyl isocyanate
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5906-35-4
1-azepanylamine
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1156-19-0
tolazamide
| Conditions | Yield |
|---|---|
|
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
|
77%
|
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1156-19-0
tolazamide
| Conditions | Yield |
|---|---|
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|
2.What is the CAS number for TOLAZAMIDE ?
The CAS number of TOLAZAMIDE is 1156-19-0.
More information of TOLAZAMIDE 1156-19-0 are:
|
CAS?Number |
1156-19-0 |
|
Density |
1.29g/cm3 |
|
Melting Point |
162-164°C |
|
Boiling Point |
°Cat760mmHg |
|
Flash Point |
°C |
|
Refractive Index |
1.6740 (estimate) |
|
HS CODE |
2935904000 |
|
PSA |
86.89000 |
|
LogP |
3.57440 |
|
Pka |
3.6(at 25℃) |
3.What are another words for TOLAZAMIDE ?
Synonyms?for?TOLAZAMIDE 1156-19-0:Urea,1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)- (6CI,7CI,8CI); 1-(4-Methylphenylsulfonyl)-3-(hexahydro-1H-azepin-1-yl)urea;1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea;1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea; Diabewas;N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea; NSC 70762; Norglycin; Tolanase;Tolazamide; Tolinase; U 17835
4.What is the molecular formula of TOLAZAMIDE?
The chemical formula of ?TOLAZAMIDE is?C14H21 N3 O3 S which containing 14 Carbon atoms,21 Hydrogen atoms,3 Nitrogen atoms,3 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??TOLAZAMIDE?is 311.405.
5.What is TOLAZAMIDE (1156-19-0) used for?
Tolazamide is a first generation sulfonylurea that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2; IC50 = 4.2 μM in HEK293 cells transfected with the human receptor). It has no effect on glucose uptake in L6 rat skeletal muscle cells when used at a concentration of 0.6 mg/mL but enhances glucose uptake two-fold when used in combination with insulin. In vivo, tolazamide (128 mg/kg) reduces glomerulosclerosis and albumin excretion in a rat model of insulin-dependent diabetes induced by streptozotocin . Formulations containing tolazamide have been used in the treatment of type 2 diabetes.
InChI:InChI=1/C14H21N3O3S/c1-12-6-8-13(9-7-12)21(19,20)16-14(18)15-17-10-4-2-3-5-11-17/h6-9H,2-5,10-11H2,1H3,(H2,15,16,18)
Relevant articles related to TOLAZAMIDE:
|
Article |
Source |
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Combinations comprising dipeptidylpeptidase-iv inhibitor |
- , (2008/06/13) |
6.Buy TOLAZAMIDE with the best price .
Jiacheng-Chem Enterprises Limited is a quality supplier of TOLAZAMIDE. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on TOLAZAMIDE 1156-19-0.
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