TOLAZAMIDE

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1.What is the TOLAZAMIDE ?

Tolazamide

Tosyl isocyanate
4083-64-1

Tosyl isocyanate

1-azepanylamine
5906-35-4

1-azepanylamine

tolazamide
1156-19-0

tolazamide

Conditions
Conditions Yield
In dichloromethane; at 20 ℃; Inert atmosphere;
77%
tolazamide
1156-19-0

tolazamide

Conditions
Conditions Yield

2.What is the CAS number for TOLAZAMIDE ?

The CAS number of TOLAZAMIDE is 1156-19-0.

More information of TOLAZAMIDE 1156-19-0 are:

CAS?Number

1156-19-0

Density

1.29g/cm3

Melting Point

162-164°C

Boiling Point

°Cat760mmHg

Flash Point

°C

Refractive Index

1.6740 (estimate)

HS CODE

2935904000

PSA

86.89000

LogP

3.57440

Pka

3.6(at 25℃)

3.What are another words for TOLAZAMIDE ?

Synonyms?for?TOLAZAMIDE 1156-19-0:Urea,1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)- (6CI,7CI,8CI); 1-(4-Methylphenylsulfonyl)-3-(hexahydro-1H-azepin-1-yl)urea;1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea;1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea; Diabewas;N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea; NSC 70762; Norglycin; Tolanase;Tolazamide; Tolinase; U 17835

4.What is the molecular formula of TOLAZAMIDE?

The chemical formula of ?TOLAZAMIDE is?C14H21 N3 O3 S which containing 14 Carbon atoms,21 Hydrogen atoms,3 Nitrogen atoms,3 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??TOLAZAMIDE?is 311.405.

5.What is TOLAZAMIDE (1156-19-0) used for?

Tolazamide is a first generation sulfonylurea that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2; IC50 = 4.2 μM in HEK293 cells transfected with the human receptor). It has no effect on glucose uptake in L6 rat skeletal muscle cells when used at a concentration of 0.6 mg/mL but enhances glucose uptake two-fold when used in combination with insulin. In vivo, tolazamide (128 mg/kg) reduces glomerulosclerosis and albumin excretion in a rat model of insulin-dependent diabetes induced by streptozotocin . Formulations containing tolazamide have been used in the treatment of type 2 diabetes.

InChI:InChI=1/C14H21N3O3S/c1-12-6-8-13(9-7-12)21(19,20)16-14(18)15-17-10-4-2-3-5-11-17/h6-9H,2-5,10-11H2,1H3,(H2,15,16,18)

Relevant articles related to TOLAZAMIDE:

Article

Source

Combinations comprising dipeptidylpeptidase-iv inhibitor

-

, (2008/06/13)

6.Buy TOLAZAMIDE with the best price .

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